The mean increase in fasting triglyceride was 71 mg dl 54 in the clozaril group and 39 mg dl 35 in the chlorpromazine group table 5 .

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High doses or long-term use of clozapine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your.

medicines to treat high blood pressure eg. propranolol.captopril medicines to treat depression eg. fluvoxamine.phenelzine antipsychotic order clozaril registry given as injections eg. flupenthixol decanoate.fluphenazine decanoate benzodiazepines or sleeping tablets eg. diazepam.temazepam antihistamines eg. terfenadine.chlorpheniramine antibiotics eg. co-trimoxazole .efaclor medicines to treat cancer eg. cyclophosphamide.ifosfamide medicines to treat epilepsy eg. phenytoin and carbamazepine medicines to treat pain eg. morphine.codeine alcohol.warfarin.cimetidine .ithium and some medicines used to treat arthritis eg. penicillamine.naproxen.indomethacin.

The following adverse reactions have been identified during post-approval use of clozapine. Because these reactions are reported voluntarily from a population of uncertain is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

In managing overdosage.consider the possibility of multiple-drug involvement.

Call your doctor right away if you have. chest pain.trouble breathing.fluttering in your chest.signs of infection (weakness.fever.sore throat.cold or flu symptoms).or if you feel like you might pass out.

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