Severe anemia must be corrected before initiating therapy with hydrea.

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Evaluate hematologic status prior to and during treatment with HYDREAProvide supportive care and modify dose or discontinue HYDREA as neededRecovery from myelosuppression is usually rapid when therapy is interrupted.

Before taking hydroxyureatell your doctor or pharmacist if you are allergic to itor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.

As hydroxyurea is mainly eliminated from the body via the kidneysdose reductions may be necessary in patients with reduced kidney function.

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concomitant use of hydrea with a live virus vaccine may potentiate the replication of the virus and or may increase the adverse reaction of the vaccine because normal defense mechanisms may be suppressed by hydrea.

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